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Colorectal cancer in Tanzania: the current status and future directions

INTRODUCTION: Globally, colorectal cancer (CRC) is the third most common malignancy and the second most common cause of cancer death. By 2030, the incidence is expected to increase to reach 2.2 million cases and 1.1 million deaths. In Sub-Saharan Africa, accurate cancer incidence data is limited, bu...

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Autores principales: Akoko, Larry, Brand, Nathan, Kotecha, Vihar, Byabato, Sam, Ndumbalo, Jerry, Mwashambwa, Masumbuko, Mwakigonja, Amos, Lowry, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310332/
https://www.ncbi.nlm.nih.gov/pubmed/37396097
http://dx.doi.org/10.3332/ecancer.2023.1564
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author Akoko, Larry
Brand, Nathan
Kotecha, Vihar
Byabato, Sam
Ndumbalo, Jerry
Mwashambwa, Masumbuko
Mwakigonja, Amos
Lowry, Ann
author_facet Akoko, Larry
Brand, Nathan
Kotecha, Vihar
Byabato, Sam
Ndumbalo, Jerry
Mwashambwa, Masumbuko
Mwakigonja, Amos
Lowry, Ann
author_sort Akoko, Larry
collection PubMed
description INTRODUCTION: Globally, colorectal cancer (CRC) is the third most common malignancy and the second most common cause of cancer death. By 2030, the incidence is expected to increase to reach 2.2 million cases and 1.1 million deaths. In Sub-Saharan Africa, accurate cancer incidence data is limited, but anecdotally, clinicians note a significant rise in the incidence of CRC in the past decade. To educate clinicians on the growing burden of CRC, the Tanzanian Surgical Association hosted a 4-day CRC symposium from 3rd to 6th October 2022. Following the meeting, a group of multidisciplinary stakeholders created a working group whose first task was to assess the epidemiology, presentation and available resources for CRC care in Tanzania. The findings of that assessment are described in this article. FINDINGS: The true incidence of CRC in Tanzania is currently unknown. However, individual high-volume centres have noted a dramatic rise in cases of colon and rectal cancer on their wards. A review of the published data on CRC in Tanzania showed that most patients present with CRC late and the limited availability of endoscopic and diagnostic services poses a challenge for accurately staging these patients prior to treatment. Multidisciplinary care, including surgery, chemotherapy and radiation, is available for the treatment of CRC in Tanzania, although the capacity and quality of these services vary throughout the country. CONCLUSION: There is a substantial burden of CRC in Tanzania that appears to be increasing. While there is capacity in the country to provide all aspects of multidisciplinary care, late presentation, limited access to diagnostic and treatment services and poor coordination continue to be significant barriers to providing optimal treatment to these patients.
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spelling pubmed-103103322023-06-30 Colorectal cancer in Tanzania: the current status and future directions Akoko, Larry Brand, Nathan Kotecha, Vihar Byabato, Sam Ndumbalo, Jerry Mwashambwa, Masumbuko Mwakigonja, Amos Lowry, Ann Ecancermedicalscience Review INTRODUCTION: Globally, colorectal cancer (CRC) is the third most common malignancy and the second most common cause of cancer death. By 2030, the incidence is expected to increase to reach 2.2 million cases and 1.1 million deaths. In Sub-Saharan Africa, accurate cancer incidence data is limited, but anecdotally, clinicians note a significant rise in the incidence of CRC in the past decade. To educate clinicians on the growing burden of CRC, the Tanzanian Surgical Association hosted a 4-day CRC symposium from 3rd to 6th October 2022. Following the meeting, a group of multidisciplinary stakeholders created a working group whose first task was to assess the epidemiology, presentation and available resources for CRC care in Tanzania. The findings of that assessment are described in this article. FINDINGS: The true incidence of CRC in Tanzania is currently unknown. However, individual high-volume centres have noted a dramatic rise in cases of colon and rectal cancer on their wards. A review of the published data on CRC in Tanzania showed that most patients present with CRC late and the limited availability of endoscopic and diagnostic services poses a challenge for accurately staging these patients prior to treatment. Multidisciplinary care, including surgery, chemotherapy and radiation, is available for the treatment of CRC in Tanzania, although the capacity and quality of these services vary throughout the country. CONCLUSION: There is a substantial burden of CRC in Tanzania that appears to be increasing. While there is capacity in the country to provide all aspects of multidisciplinary care, late presentation, limited access to diagnostic and treatment services and poor coordination continue to be significant barriers to providing optimal treatment to these patients. Cancer Intelligence 2023-06-22 /pmc/articles/PMC10310332/ /pubmed/37396097 http://dx.doi.org/10.3332/ecancer.2023.1564 Text en © the authors; licensee ecancermedicalscience. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Akoko, Larry
Brand, Nathan
Kotecha, Vihar
Byabato, Sam
Ndumbalo, Jerry
Mwashambwa, Masumbuko
Mwakigonja, Amos
Lowry, Ann
Colorectal cancer in Tanzania: the current status and future directions
title Colorectal cancer in Tanzania: the current status and future directions
title_full Colorectal cancer in Tanzania: the current status and future directions
title_fullStr Colorectal cancer in Tanzania: the current status and future directions
title_full_unstemmed Colorectal cancer in Tanzania: the current status and future directions
title_short Colorectal cancer in Tanzania: the current status and future directions
title_sort colorectal cancer in tanzania: the current status and future directions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310332/
https://www.ncbi.nlm.nih.gov/pubmed/37396097
http://dx.doi.org/10.3332/ecancer.2023.1564
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