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Efficiently quantifying DNA methylation for bulk- and single-cell bisulfite data
MOTIVATION: DNA CpG methylation (CpGm) has proven to be a crucial epigenetic factor in the mammalian gene regulatory system. Assessment of DNA CpG methylation values via whole-genome bisulfite sequencing (WGBS) is, however, computationally extremely demanding. RESULTS: We present FAst MEthylation ca...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310462/ https://www.ncbi.nlm.nih.gov/pubmed/37326968 http://dx.doi.org/10.1093/bioinformatics/btad386 |