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Efficiently quantifying DNA methylation for bulk- and single-cell bisulfite data

MOTIVATION: DNA CpG methylation (CpGm) has proven to be a crucial epigenetic factor in the mammalian gene regulatory system. Assessment of DNA CpG methylation values via whole-genome bisulfite sequencing (WGBS) is, however, computationally extremely demanding. RESULTS: We present FAst MEthylation ca...

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Detalles Bibliográficos
Autores principales:	Fischer, Jonas, Schulz, Marcel H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310462/ https://www.ncbi.nlm.nih.gov/pubmed/37326968 http://dx.doi.org/10.1093/bioinformatics/btad386

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