A Rare Case of Disseminated Histoplasmosis in an Adult With Alcoholic Liver Cirrhosis

Histoplasmosis, also known as "Darling’s disease," is caused by the dimorphic fungus Histoplasma capsulatum, which is distributed all over the world but is more common in Northern America. In this paper, we present the case of an adult patient with decompensated liver cirrhosis who had pos...

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Autores principales: Kozyk, Marko, Strubchevska, Kateryna, Szela, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Gastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310550/
https://www.ncbi.nlm.nih.gov/pubmed/37398709
http://dx.doi.org/10.7759/cureus.39744
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author Kozyk, Marko
Strubchevska, Kateryna
Szela, John
author_facet Kozyk, Marko
Strubchevska, Kateryna
Szela, John
author_sort Kozyk, Marko
collection PubMed
description Histoplasmosis, also known as "Darling’s disease," is caused by the dimorphic fungus Histoplasma capsulatum, which is distributed all over the world but is more common in Northern America. In this paper, we present the case of an adult patient with decompensated liver cirrhosis who had positive antigen test results for H. capsulatum and Blastomyces dermatitidis. Disseminated histoplasmosis was confirmed by means of additional antibody testing in a patient with septic shock complicated by multiorgan failure and duodenal perforation. A high index of suspicion is required for the detection of disseminated histoplasmosis.
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spelling pubmed-103105502023-07-01 A Rare Case of Disseminated Histoplasmosis in an Adult With Alcoholic Liver Cirrhosis Kozyk, Marko Strubchevska, Kateryna Szela, John Cureus Gastroenterology Histoplasmosis, also known as "Darling’s disease," is caused by the dimorphic fungus Histoplasma capsulatum, which is distributed all over the world but is more common in Northern America. In this paper, we present the case of an adult patient with decompensated liver cirrhosis who had positive antigen test results for H. capsulatum and Blastomyces dermatitidis. Disseminated histoplasmosis was confirmed by means of additional antibody testing in a patient with septic shock complicated by multiorgan failure and duodenal perforation. A high index of suspicion is required for the detection of disseminated histoplasmosis. Cureus 2023-05-30 /pmc/articles/PMC10310550/ /pubmed/37398709 http://dx.doi.org/10.7759/cureus.39744 Text en Copyright © 2023, Kozyk et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Kozyk, Marko
Strubchevska, Kateryna
Szela, John
A Rare Case of Disseminated Histoplasmosis in an Adult With Alcoholic Liver Cirrhosis
title A Rare Case of Disseminated Histoplasmosis in an Adult With Alcoholic Liver Cirrhosis
title_full A Rare Case of Disseminated Histoplasmosis in an Adult With Alcoholic Liver Cirrhosis
title_fullStr A Rare Case of Disseminated Histoplasmosis in an Adult With Alcoholic Liver Cirrhosis
title_full_unstemmed A Rare Case of Disseminated Histoplasmosis in an Adult With Alcoholic Liver Cirrhosis
title_short A Rare Case of Disseminated Histoplasmosis in an Adult With Alcoholic Liver Cirrhosis
title_sort rare case of disseminated histoplasmosis in an adult with alcoholic liver cirrhosis
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310550/
https://www.ncbi.nlm.nih.gov/pubmed/37398709
http://dx.doi.org/10.7759/cureus.39744
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