Dissecting the roles of MBD2 isoforms and domains in regulating NuRD complex function during cellular differentiation

The Nucleosome Remodeling and Deacetylation (NuRD) complex is a crucial regulator of cellular differentiation. Two members of the Methyl-CpG-binding domain (MBD) protein family, MBD2 and MBD3, are known to be integral, but mutually exclusive subunits of the NuRD complex. Several MBD2 and MBD3 isofor...

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Detalles Bibliográficos
Autores principales: Schmolka, Nina, Karemaker, Ino D., Cardoso da Silva, Richard, Recchia, Davide C., Spegg, Vincent, Bhaskaran, Jahnavi, Teske, Michael, de Wagenaar, Nathalie P., Altmeyer, Matthias, Baubec, Tuncay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310694/
https://www.ncbi.nlm.nih.gov/pubmed/37385984
http://dx.doi.org/10.1038/s41467-023-39551-w

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