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Biallelic FBXW7 knockout induces AKAP8-mediated DNA damage in neighbouring wildtype cells

Colorectal cancer possesses marked intratumoral heterogeneity. While subclonal interactions between Vogelstein driver mutations have been extensively studied, less is known about competitive or cooperative effects between subclonal populations with other cancer driver mutations. FBXW7 is a cancer dr...

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Detalles Bibliográficos
Autores principales:	Chan, Dedrick Kok Hong, Mandal, Amit, Hester, Svenja, Yu, Zhanru, Higgins, Geoff Stuart, Kessler, Benedikt Mathias, Fischer, Roman, Buczacki, Simon James Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310709/ https://www.ncbi.nlm.nih.gov/pubmed/37386001 http://dx.doi.org/10.1038/s41420-023-01494-y

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