Botulinum neurotoxin A ameliorates depressive-like behavior in a reserpine-induced Parkinson’s disease mouse model via suppressing hippocampal microglial engulfment and neuroinflammation

Depression is one of the common non-motor symptoms of Parkinson’s disease (PD). In the clinic, botulinum neurotoxin A (BoNT/A) has been used to treat depression. In this study, we investigated the mechanisms underlying the anti-depressive effect of BoNT/A in a PD mouse model. Mice were administered...

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Detalles Bibliográficos
Autores principales: Li, Yang, Yin, Qiao, Li, Qi, Huo, An-ran, Shen, Ting-ting, Cao, Jia-qian, Liu, Chun-feng, Liu, Tong, Luo, Wei-feng, Cong, Qi-fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310724/
https://www.ncbi.nlm.nih.gov/pubmed/36765267
http://dx.doi.org/10.1038/s41401-023-01058-x

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