20(S)- Protopanaxadiol suppresses hepatic stellate cell activation via WIF1 demethylation-mediated inactivation of the Wnt/β-catenin pathway

BACKGROUND: 20(S)-protopanaxadiol (PPD), one of the main components of ginseng, has anti-inflammatory, anti-estrogenic, and anti-tumor activities. It is known that activated hepatic stellate cells (HSCs) are the primary producers of extracellular matrix (ECM) in the liver, and the Wnt/β-catenin path...

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Detalles Bibliográficos
Autores principales: Li, Chunxue, Zhan, Yating, Zhang, Rongrong, Tao, Qiqi, Lang, Zhichao, Zheng, Jianjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310761/
https://www.ncbi.nlm.nih.gov/pubmed/37397420
http://dx.doi.org/10.1016/j.jgr.2022.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310761/
https://www.ncbi.nlm.nih.gov/pubmed/37397420
http://dx.doi.org/10.1016/j.jgr.2022.05.005

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