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Neurokinin-1 receptor drives PKCɑ-AURKA/N-Myc signaling to facilitate the neuroendocrine progression of prostate cancer

The widespread application of antiandrogen therapies has aroused a significant increase in the incidence of NEPC, a lethal form of the disease lacking efficient clinical treatments. Here we identified a cell surface receptor neurokinin-1 (NK1R) as a clinically relevant driver of treatment-related NE...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiao-Wei, Li, Jing-Yi, Li, Lin, Hu, Wen-Qian, Tao, Yan, Gao, Wen-Yan, Ye, Zi-Nuo, Jia, Hao-Yuan, Wang, Jia-Nan, Miao, Xiao-Kang, Yang, Wen-Le, Wang, Rui, Mou, Ling-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310825/ https://www.ncbi.nlm.nih.gov/pubmed/37385990 http://dx.doi.org/10.1038/s41419-023-05894-x

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