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Reduction in disialyl-T antigen levels in mice deficient for both St6galnac3 and St6galnac4 results in blood filling of lymph nodes

Sialic acid (SA) is present at the terminal ends of carbohydrate chains in glycoproteins and glycolipids and is involved in various biological phenomena. The biological function of the disialyl-T (SAα2-3Galβ1-3(SAα2-6)GalNAcα1-O-Ser/Thr) structure is largely unknown. To elucidate the role of disialy...

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Detalles Bibliográficos
Autores principales: Fuseya, Sayaka, Izumi, Hiroyuki, Hamano, Ayane, Murakami, Yuka, Suzuki, Riku, Koiwai, Rikako, Hayashi, Takuto, Kuno, Atsushi, Takahashi, Satoru, Kudo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310836/
https://www.ncbi.nlm.nih.gov/pubmed/37386100
http://dx.doi.org/10.1038/s41598-023-37363-y