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Divalent cations in human liver pyruvate kinase exemplify the combined effects of complex-equilibrium and allosteric regulation
There is growing recognition that the functional outcome of binding of an allosteric regulator to a protein/enzyme is influenced by the presence of other ligands. Here, this complexity is exemplified in the allosteric regulation of human liver pyruvate kinase (hLPYK) that is influenced by the presen...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310847/ https://www.ncbi.nlm.nih.gov/pubmed/37386072 http://dx.doi.org/10.1038/s41598-023-36943-2 |