A human proteogenomic-cellular framework identifies KIF5A as a modulator of astrocyte process integrity with relevance to ALS

Genome-wide association studies identified several disease-causing mutations in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). However, the contribution of genetic variants to pathway disturbances and their cell type-specific variations, especially in glia, is poorly unde...

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Detalles Bibliográficos
Autores principales: Szebényi, Kornélia, Barrio-Hernandez, Inigo, Gibbons, George M., Biasetti, Luca, Troakes, Claire, Beltrao, Pedro, Lakatos, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310856/
https://www.ncbi.nlm.nih.gov/pubmed/37386082
http://dx.doi.org/10.1038/s42003-023-05041-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310856/
https://www.ncbi.nlm.nih.gov/pubmed/37386082
http://dx.doi.org/10.1038/s42003-023-05041-4

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