Cargando…

Meridian energy analysis may predict the prognosis of patients with advanced cancers receiving palliative care

BACKGROUND AND AIM: A better understanding of irreversible prognoses in palliative care is crucial for improving patients’ quality of life and their sense of dignity. We examined whether measurements of meridian electrical conductance can noninvasively and objectively predict survival time in a hosp...

Descripción completa

Detalles Bibliográficos
Autores principales: Chung, Ming-Cheng, Tsai, Pei-Yu, Chen, Chun-Min, Yang, Chueh-Ko, Chang, Hen-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310863/
https://www.ncbi.nlm.nih.gov/pubmed/37396153
http://dx.doi.org/10.1016/j.jtcme.2023.03.003
_version_ 1785066624368246784
author Chung, Ming-Cheng
Tsai, Pei-Yu
Chen, Chun-Min
Yang, Chueh-Ko
Chang, Hen-Hong
author_facet Chung, Ming-Cheng
Tsai, Pei-Yu
Chen, Chun-Min
Yang, Chueh-Ko
Chang, Hen-Hong
author_sort Chung, Ming-Cheng
collection PubMed
description BACKGROUND AND AIM: A better understanding of irreversible prognoses in palliative care is crucial for improving patients’ quality of life and their sense of dignity. We examined whether measurements of meridian electrical conductance can noninvasively and objectively predict survival time in a hospice patient population. EXPERIMENTAL PROCEDURE: This was a single-center cohort study. Between 2019 and 2020, we measured skin conductance from 24 representative acupoints of 12 meridians on both sides of the body in 181 advanced cancer patients within 48 h of hospitalization and monitored their survival time. The Palliative Prognostic Score (PaP Score) was calculated for each patient, classifying them into one of three prognosis groups: Group A, B, or C. Factors associated with short-term and long-term survival were identified using multivariate regression analysis. Statistical differences in survival times were analyzed between the meridian electrical conductance measurements and PaP Scores. RESULTS AND CONCLUSION: Analyses of the clinicopathological data from terminal cancer patients revealed that male sex, mean meridian electrical conductance measurements of ≤8.8 μA, and PaP Scores in Group C were independent predictors of short-term survival. Mean meridian electrical conductance measurements of ≤8.8 μA demonstrated good sensitivity (85.1%) and adequate specificity (60.6%) for short-term survival. A survival curve analysis revealed a mortality rate of 90.6% at 30 days among patients with meridian electrical conductance measurements of ≤8.8 μA. A mean meridian electrical conductance measurement of ≤8.8 μA can objectively assess short-term survival with advanced cancer and reduce nonbeneficial medical treatment.
format Online
Article
Text
id pubmed-10310863
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-103108632023-07-01 Meridian energy analysis may predict the prognosis of patients with advanced cancers receiving palliative care Chung, Ming-Cheng Tsai, Pei-Yu Chen, Chun-Min Yang, Chueh-Ko Chang, Hen-Hong J Tradit Complement Med Article BACKGROUND AND AIM: A better understanding of irreversible prognoses in palliative care is crucial for improving patients’ quality of life and their sense of dignity. We examined whether measurements of meridian electrical conductance can noninvasively and objectively predict survival time in a hospice patient population. EXPERIMENTAL PROCEDURE: This was a single-center cohort study. Between 2019 and 2020, we measured skin conductance from 24 representative acupoints of 12 meridians on both sides of the body in 181 advanced cancer patients within 48 h of hospitalization and monitored their survival time. The Palliative Prognostic Score (PaP Score) was calculated for each patient, classifying them into one of three prognosis groups: Group A, B, or C. Factors associated with short-term and long-term survival were identified using multivariate regression analysis. Statistical differences in survival times were analyzed between the meridian electrical conductance measurements and PaP Scores. RESULTS AND CONCLUSION: Analyses of the clinicopathological data from terminal cancer patients revealed that male sex, mean meridian electrical conductance measurements of ≤8.8 μA, and PaP Scores in Group C were independent predictors of short-term survival. Mean meridian electrical conductance measurements of ≤8.8 μA demonstrated good sensitivity (85.1%) and adequate specificity (60.6%) for short-term survival. A survival curve analysis revealed a mortality rate of 90.6% at 30 days among patients with meridian electrical conductance measurements of ≤8.8 μA. A mean meridian electrical conductance measurement of ≤8.8 μA can objectively assess short-term survival with advanced cancer and reduce nonbeneficial medical treatment. Elsevier 2023-03-02 /pmc/articles/PMC10310863/ /pubmed/37396153 http://dx.doi.org/10.1016/j.jtcme.2023.03.003 Text en © 2023 Center for Food and Biomolecules, National Taiwan University. Production and hosting by Elsevier Taiwan LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Chung, Ming-Cheng
Tsai, Pei-Yu
Chen, Chun-Min
Yang, Chueh-Ko
Chang, Hen-Hong
Meridian energy analysis may predict the prognosis of patients with advanced cancers receiving palliative care
title Meridian energy analysis may predict the prognosis of patients with advanced cancers receiving palliative care
title_full Meridian energy analysis may predict the prognosis of patients with advanced cancers receiving palliative care
title_fullStr Meridian energy analysis may predict the prognosis of patients with advanced cancers receiving palliative care
title_full_unstemmed Meridian energy analysis may predict the prognosis of patients with advanced cancers receiving palliative care
title_short Meridian energy analysis may predict the prognosis of patients with advanced cancers receiving palliative care
title_sort meridian energy analysis may predict the prognosis of patients with advanced cancers receiving palliative care
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310863/
https://www.ncbi.nlm.nih.gov/pubmed/37396153
http://dx.doi.org/10.1016/j.jtcme.2023.03.003
work_keys_str_mv AT chungmingcheng meridianenergyanalysismaypredicttheprognosisofpatientswithadvancedcancersreceivingpalliativecare
AT tsaipeiyu meridianenergyanalysismaypredicttheprognosisofpatientswithadvancedcancersreceivingpalliativecare
AT chenchunmin meridianenergyanalysismaypredicttheprognosisofpatientswithadvancedcancersreceivingpalliativecare
AT yangchuehko meridianenergyanalysismaypredicttheprognosisofpatientswithadvancedcancersreceivingpalliativecare
AT changhenhong meridianenergyanalysismaypredicttheprognosisofpatientswithadvancedcancersreceivingpalliativecare