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Ginsenoside Rg1 Epigenetically Modulates Smad7 Expression in Liver Fibrosis via MicroRNA-152

BACKGROUND: Ginsenoside Rg1, a bioactive component of Ginseng, has demonstrated anti-inflammatory, anti-cancer, and hepatoprotective effects. It is known that the epithelial–mesenchymal transition (EMT) plays a key role in the activation of hepatic stellate cells (HSCs). Recently, Rg1 has been shown...

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Detalles Bibliográficos
Autores principales: Zhang, Rongrong, Li, Xinmiao, Gao, Yuxiang, Tao, Qiqi, Lang, Zhichao, Zhan, Yating, Li, Chunxue, Zheng, Jianjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310870/
https://www.ncbi.nlm.nih.gov/pubmed/37397418
http://dx.doi.org/10.1016/j.jgr.2022.12.005

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