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Proteasome-dependent senescent tumor cells mediate immunosuppression through CCL20 secretion and M2 polarization in pancreatic ductal adenocarcinoma

The outcome of pancreatic ductal adenocarcinoma (PDAC) remains poor due to few therapeutic options available and challenges with precision therapy to target each tumour’s specific characteristics. In this study, a biologically meaningful patient stratification-prognostic model with therapeutic sugge...

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Detalles Bibliográficos
Autores principales:	Wu, Mengwei, Han, Jiashu, Wu, Hao, Liu, Ziwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310997/ https://www.ncbi.nlm.nih.gov/pubmed/37398643 http://dx.doi.org/10.3389/fimmu.2023.1216376

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