PLSCR1 promotes apoptosis and clearance of retinal ganglion cells in glaucoma pathogenesis

Glaucoma is the leading cause of irreversible blindness worldwide. In the pathogenesis of glaucoma, activated microglia can lead to retinal ganglion cells (RGCs) apoptosis and death, however, the molecular mechanisms remain largely unknown. We demonstrate that phospholipid scramblase 1 (PLSCR1) is a...

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Detalles Bibliográficos
Autores principales: Luo, Jingyi, Lian, Qing, Zhu, Deliang, Zhao, Minglei, Mei, Tingfang, Shang, Bizhi, Yang, Zeqiu, Liu, Chujun, Xu, Wenchang, Zhou, Lan, Wu, Keling, Liu, Xinqi, Lai, Yuhua, Mao, Fuxiang, Li, Weihua, Zuo, Chengguo, Zhang, Kang, Lin, Mingkai, Zhuo, Yehong, Liu, Yizhi, Lu, Lin, Zhao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311034/
https://www.ncbi.nlm.nih.gov/pubmed/37397520
http://dx.doi.org/10.1016/j.gendis.2022.05.036

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