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Transcriptome analysis of CD4(+) T cells from HIV-infected individuals receiving ART with LLV revealed novel transcription factors regulating HIV-1 promoter activity

Some HIV-infected individuals receiving ART develop low-level viremia (LLV), with a plasma viral load of 50–1000 copies/mL. Persistent low-level viremia is associated with subsequent virologic failure. The peripheral blood CD4(+) T cell pool is a source of LLV. However, the intrinsic characteristics...

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Detalles Bibliográficos
Autores principales: Chen, Jingliang, He, Yaozu, Zhong, Huolin, Hu, Fengyu, Li, Yonghong, Zhang, Yeyang, Zhang, Xia, Lin, Weiyin, Li, Quanmin, Xu, Feilong, Chen, Shaozhen, Zhang, Hui, Cai, Weiping, Li, Linghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311176/
https://www.ncbi.nlm.nih.gov/pubmed/36907331
http://dx.doi.org/10.1016/j.virs.2023.03.001