Cargando…

Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp.

The objective of the study was to investigate the effects of a dacitic tuff breccia (DTB) on Eimeria-infected broilers. A total of 600 one-day-old Cobb 500 male chickens were randomly assigned to 5 treatments with 10 replicates of 12 birds. Treatments were: an unchallenged control (UC), a challenged...

Descripción completa

Detalles Bibliográficos
Autores principales: Teng, P.-Y., Choi, J., Yadav, S., Marshall, B., Castro, F.L.S., Ferrel, J., Kim, W.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311180/
https://www.ncbi.nlm.nih.gov/pubmed/37141812
http://dx.doi.org/10.1016/j.psj.2023.102697
_version_ 1785066687327895552
author Teng, P.-Y.
Choi, J.
Yadav, S.
Marshall, B.
Castro, F.L.S.
Ferrel, J.
Kim, W.K.
author_facet Teng, P.-Y.
Choi, J.
Yadav, S.
Marshall, B.
Castro, F.L.S.
Ferrel, J.
Kim, W.K.
author_sort Teng, P.-Y.
collection PubMed
description The objective of the study was to investigate the effects of a dacitic tuff breccia (DTB) on Eimeria-infected broilers. A total of 600 one-day-old Cobb 500 male chickens were randomly assigned to 5 treatments with 10 replicates of 12 birds. Treatments were: an unchallenged control (UC), a challenged (CC) control (0% DTB), and 3 challenged groups with 0.125, 0.25, or 0.5% DTB. At d 14, birds in the CC and DTB groups were orally gavaged with mixed Eimeria spp., while the UC received water. Growth performance was evaluated during prechallenge, challenge, and postchallenge periods (0–14 d; 14–20 d; and 20–26 d, respectively). Gastrointestinal permeability was measured at 5 days postinfection (dpi). Intestinal histology and nutrient digestibility of dry matter (DM), crude protein (CP), and ileal digestible energy (IDE) were measured at 6 dpi. Liver activity of glutathione peroxidase (GSH-Px) was determined at 6 dpi, and concentrations of reduced (GSH) and oxidized glutathione (GSSG) were analyzed at 6 and 12 dpi. Data were analyzed using a linear mixed model analysis and Tukey's test (P ≤ 0.05). From 0 to 14 d, similar average daily gain (ADG) and average daily feed intake (ADFI, P > 0.05) were observed. Gain:feed ratio (GF) was higher in 0.125, 0.25, and 0.5% of DTB than the CC and UC (P < 0.001). From 14 to 20 d, the UC had the highest ADG, ADFI, and GF (P < 0.001). At 5 dpi, intestinal permeability was higher in the challenged groups than the UC. Additionally, the UC showed the highest apparent ileal digestibility of CP, whereas 0.125% DTB had higher CP digestibility than the CC and 0.5% DTB (P < 0.001). At 6 dpi, 0.125% DTB increased GSH-Px activity compared to the CC, 0.5% DTB, and UC (P < 0.001). At 12 dpi, 0.125% DTB showed increased GSH concentration compared to the CC, 0.25% DTB, and 0.5% DTB (P < 0.01). The mild coccidia infection negatively impacted growth performance, apparent ileal nutrient digestibility, intestinal histology, and gastrointestinal integrity in broilers. The use of 0.125% DTB exhibited potential in improving antioxidant responses, apparent ileal digestibility of CP, and growth performance.
format Online
Article
Text
id pubmed-10311180
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-103111802023-07-01 Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp. Teng, P.-Y. Choi, J. Yadav, S. Marshall, B. Castro, F.L.S. Ferrel, J. Kim, W.K. Poult Sci METABOLISM AND NUTRITION The objective of the study was to investigate the effects of a dacitic tuff breccia (DTB) on Eimeria-infected broilers. A total of 600 one-day-old Cobb 500 male chickens were randomly assigned to 5 treatments with 10 replicates of 12 birds. Treatments were: an unchallenged control (UC), a challenged (CC) control (0% DTB), and 3 challenged groups with 0.125, 0.25, or 0.5% DTB. At d 14, birds in the CC and DTB groups were orally gavaged with mixed Eimeria spp., while the UC received water. Growth performance was evaluated during prechallenge, challenge, and postchallenge periods (0–14 d; 14–20 d; and 20–26 d, respectively). Gastrointestinal permeability was measured at 5 days postinfection (dpi). Intestinal histology and nutrient digestibility of dry matter (DM), crude protein (CP), and ileal digestible energy (IDE) were measured at 6 dpi. Liver activity of glutathione peroxidase (GSH-Px) was determined at 6 dpi, and concentrations of reduced (GSH) and oxidized glutathione (GSSG) were analyzed at 6 and 12 dpi. Data were analyzed using a linear mixed model analysis and Tukey's test (P ≤ 0.05). From 0 to 14 d, similar average daily gain (ADG) and average daily feed intake (ADFI, P > 0.05) were observed. Gain:feed ratio (GF) was higher in 0.125, 0.25, and 0.5% of DTB than the CC and UC (P < 0.001). From 14 to 20 d, the UC had the highest ADG, ADFI, and GF (P < 0.001). At 5 dpi, intestinal permeability was higher in the challenged groups than the UC. Additionally, the UC showed the highest apparent ileal digestibility of CP, whereas 0.125% DTB had higher CP digestibility than the CC and 0.5% DTB (P < 0.001). At 6 dpi, 0.125% DTB increased GSH-Px activity compared to the CC, 0.5% DTB, and UC (P < 0.001). At 12 dpi, 0.125% DTB showed increased GSH concentration compared to the CC, 0.25% DTB, and 0.5% DTB (P < 0.01). The mild coccidia infection negatively impacted growth performance, apparent ileal nutrient digestibility, intestinal histology, and gastrointestinal integrity in broilers. The use of 0.125% DTB exhibited potential in improving antioxidant responses, apparent ileal digestibility of CP, and growth performance. Elsevier 2023-04-06 /pmc/articles/PMC10311180/ /pubmed/37141812 http://dx.doi.org/10.1016/j.psj.2023.102697 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle METABOLISM AND NUTRITION
Teng, P.-Y.
Choi, J.
Yadav, S.
Marshall, B.
Castro, F.L.S.
Ferrel, J.
Kim, W.K.
Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp.
title Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp.
title_full Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp.
title_fullStr Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp.
title_full_unstemmed Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp.
title_short Evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with Eimeria spp.
title_sort evaluation of a dacitic (rhyolitic) tuff breccia use on performance, inflammatory, and antioxidant responses in broilers mildly challenged with eimeria spp.
topic METABOLISM AND NUTRITION
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311180/
https://www.ncbi.nlm.nih.gov/pubmed/37141812
http://dx.doi.org/10.1016/j.psj.2023.102697
work_keys_str_mv AT tengpy evaluationofadaciticrhyolitictuffbrecciauseonperformanceinflammatoryandantioxidantresponsesinbroilersmildlychallengedwitheimeriaspp
AT choij evaluationofadaciticrhyolitictuffbrecciauseonperformanceinflammatoryandantioxidantresponsesinbroilersmildlychallengedwitheimeriaspp
AT yadavs evaluationofadaciticrhyolitictuffbrecciauseonperformanceinflammatoryandantioxidantresponsesinbroilersmildlychallengedwitheimeriaspp
AT marshallb evaluationofadaciticrhyolitictuffbrecciauseonperformanceinflammatoryandantioxidantresponsesinbroilersmildlychallengedwitheimeriaspp
AT castrofls evaluationofadaciticrhyolitictuffbrecciauseonperformanceinflammatoryandantioxidantresponsesinbroilersmildlychallengedwitheimeriaspp
AT ferrelj evaluationofadaciticrhyolitictuffbrecciauseonperformanceinflammatoryandantioxidantresponsesinbroilersmildlychallengedwitheimeriaspp
AT kimwk evaluationofadaciticrhyolitictuffbrecciauseonperformanceinflammatoryandantioxidantresponsesinbroilersmildlychallengedwitheimeriaspp