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Efficient full Monte Carlo modelling and multi-energy generative model development of an advanced X-ray device

Monte Carlo (MC) simulations of X-ray image devices require splitting the simulation into two parts (i.e. the generation of x-rays and the actual imaging). The X-ray production remains unchanged for repeated imaging and can thus be stored in phase space (PhS) files and used for subsequent MC simulat...

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Autores principales: Fuchs, Hermann, Zimmermann, Lukas, Reisz, Niklas, Zeilinger, Markus, Ableitinger, Alexander, Georg, Dietmar, Kuess, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311273/
https://www.ncbi.nlm.nih.gov/pubmed/35688672
http://dx.doi.org/10.1016/j.zemedi.2022.04.006
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author Fuchs, Hermann
Zimmermann, Lukas
Reisz, Niklas
Zeilinger, Markus
Ableitinger, Alexander
Georg, Dietmar
Kuess, Peter
author_facet Fuchs, Hermann
Zimmermann, Lukas
Reisz, Niklas
Zeilinger, Markus
Ableitinger, Alexander
Georg, Dietmar
Kuess, Peter
author_sort Fuchs, Hermann
collection PubMed
description Monte Carlo (MC) simulations of X-ray image devices require splitting the simulation into two parts (i.e. the generation of x-rays and the actual imaging). The X-ray production remains unchanged for repeated imaging and can thus be stored in phase space (PhS) files and used for subsequent MC simulations. Especially for medical images these dedicated PhS files require a large amount of data storage, which is partly why Generative Adversarial Networks (GANs) were recently introduced. We enhanced the approach by a conditional GAN to model multiple energies using one network. This study compares the use of PhSs, GANs, and conditional GANs as photon source with measurements. An X-ray -based imaging system (i.e. ImagingRing) was modelled in this study. half-value layers (HVLs), focal spot, and Heel effect were measured for subsequent comparison. MC simulations were performed with GATE-RTion v 1.0 considering the geometry and materials of the imaging system with vendor specific schematics. A traditional GAN model as well as the favourable conditional GAN was implemented for PhS generation. Results of the MC simulation were in agreement with the measurements regarding HVL, focal spot, and Heel effect. The conditional GAN performed best with a non-saturated loss function with R1 regularisation and gave similarly results as the traditional GAN approach. GANs proved to be superior to the PhS approach in terms of data storage and calculation overhead. Moreover, a conditional GAN enabled an energy interpolation to separate the network training process from the final required X-ray energies.
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spelling pubmed-103112732023-07-01 Efficient full Monte Carlo modelling and multi-energy generative model development of an advanced X-ray device Fuchs, Hermann Zimmermann, Lukas Reisz, Niklas Zeilinger, Markus Ableitinger, Alexander Georg, Dietmar Kuess, Peter Z Med Phys Original Paper Monte Carlo (MC) simulations of X-ray image devices require splitting the simulation into two parts (i.e. the generation of x-rays and the actual imaging). The X-ray production remains unchanged for repeated imaging and can thus be stored in phase space (PhS) files and used for subsequent MC simulations. Especially for medical images these dedicated PhS files require a large amount of data storage, which is partly why Generative Adversarial Networks (GANs) were recently introduced. We enhanced the approach by a conditional GAN to model multiple energies using one network. This study compares the use of PhSs, GANs, and conditional GANs as photon source with measurements. An X-ray -based imaging system (i.e. ImagingRing) was modelled in this study. half-value layers (HVLs), focal spot, and Heel effect were measured for subsequent comparison. MC simulations were performed with GATE-RTion v 1.0 considering the geometry and materials of the imaging system with vendor specific schematics. A traditional GAN model as well as the favourable conditional GAN was implemented for PhS generation. Results of the MC simulation were in agreement with the measurements regarding HVL, focal spot, and Heel effect. The conditional GAN performed best with a non-saturated loss function with R1 regularisation and gave similarly results as the traditional GAN approach. GANs proved to be superior to the PhS approach in terms of data storage and calculation overhead. Moreover, a conditional GAN enabled an energy interpolation to separate the network training process from the final required X-ray energies. Elsevier 2022-06-07 /pmc/articles/PMC10311273/ /pubmed/35688672 http://dx.doi.org/10.1016/j.zemedi.2022.04.006 Text en © 2022 Published by Elsevier GmbH on behalf of DGMP, ÖGMP and SSRMP. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Paper
Fuchs, Hermann
Zimmermann, Lukas
Reisz, Niklas
Zeilinger, Markus
Ableitinger, Alexander
Georg, Dietmar
Kuess, Peter
Efficient full Monte Carlo modelling and multi-energy generative model development of an advanced X-ray device
title Efficient full Monte Carlo modelling and multi-energy generative model development of an advanced X-ray device
title_full Efficient full Monte Carlo modelling and multi-energy generative model development of an advanced X-ray device
title_fullStr Efficient full Monte Carlo modelling and multi-energy generative model development of an advanced X-ray device
title_full_unstemmed Efficient full Monte Carlo modelling and multi-energy generative model development of an advanced X-ray device
title_short Efficient full Monte Carlo modelling and multi-energy generative model development of an advanced X-ray device
title_sort efficient full monte carlo modelling and multi-energy generative model development of an advanced x-ray device
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311273/
https://www.ncbi.nlm.nih.gov/pubmed/35688672
http://dx.doi.org/10.1016/j.zemedi.2022.04.006
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