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Spastin is required for human immunodeficiency virus-1 efficient replication through cooperation with the endosomal sorting complex required for transport (ESCRT) protein

Human immunodeficiency virus-1 (HIV-1) encodes simply 15 proteins and thus depends on multiple host cellular factors for virus reproduction. Spastin, a microtubule severing protein, is an identified HIV-1 dependency factor, but the mechanism regulating HIV-1 is unclear. Here, the study showed that k...

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Detalles Bibliográficos
Autores principales: Shen, Wenyuan, Liu, Chang, Hu, Yue, Ding, Qian, Feng, Jiabin, Liu, Zhou, Kong, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311276/
https://www.ncbi.nlm.nih.gov/pubmed/37172824
http://dx.doi.org/10.1016/j.virs.2023.05.006