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Deep Local Analysis deconstructs protein–protein interfaces and accurately estimates binding affinity changes upon mutation
MOTIVATION: The spectacular recent advances in protein and protein complex structure prediction hold promise for reconstructing interactomes at large-scale and residue resolution. Beyond determining the 3D arrangement of interacting partners, modeling approaches should be able to unravel the impact...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311296/ https://www.ncbi.nlm.nih.gov/pubmed/37387162 http://dx.doi.org/10.1093/bioinformatics/btad231 |