Foreign RNA spike-ins enable accurate allele-specific expression analysis at scale

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MOTIVATION: Analysis of allele-specific expression is strongly affected by the technical noise present in RNA-seq experiments. Previously, we showed that technical replicates can be used for precise estimates of this noise, and we provided a tool for correction of technical noise in allele-specific...

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Detalles Bibliográficos
Autores principales: Mendelevich, Asia, Gupta, Saumya, Pakharev, Aleksei, Teodosiadis, Athanasios, Mironov, Andrey A, Gimelbrant, Alexander A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regulatory and Functional Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311301/
https://www.ncbi.nlm.nih.gov/pubmed/37387154
http://dx.doi.org/10.1093/bioinformatics/btad254

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