Deep statistical modelling of nanopore sequencing translocation times reveals latent non-B DNA structures

MOTIVATION: Non-canonical (or non-B) DNA are genomic regions whose three-dimensional conformation deviates from the canonical double helix. Non-B DNA play an important role in basic cellular processes and are associated with genomic instability, gene regulation, and oncogenesis. Experimental methods...

Descripción completa

Detalles Bibliográficos
Autores principales: Hosseini, Marjan, Palmer, Aaron, Manka, William, Grady, Patrick G S, Patchigolla, Venkata, Bi, Jinbo, O’Neill, Rachel J, Chi, Zhiyi, Aguiar, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Sequence Analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311326/
https://www.ncbi.nlm.nih.gov/pubmed/37387144
http://dx.doi.org/10.1093/bioinformatics/btad220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311326/
https://www.ncbi.nlm.nih.gov/pubmed/37387144
http://dx.doi.org/10.1093/bioinformatics/btad220

Ejemplares similares