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Deep statistical modelling of nanopore sequencing translocation times reveals latent non-B DNA structures

MOTIVATION: Non-canonical (or non-B) DNA are genomic regions whose three-dimensional conformation deviates from the canonical double helix. Non-B DNA play an important role in basic cellular processes and are associated with genomic instability, gene regulation, and oncogenesis. Experimental methods...

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Detalles Bibliográficos
Autores principales:	Hosseini, Marjan, Palmer, Aaron, Manka, William, Grady, Patrick G S, Patchigolla, Venkata, Bi, Jinbo, O’Neill, Rachel J, Chi, Zhiyi, Aguiar, Derek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Genome Sequence Analysis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311326/ https://www.ncbi.nlm.nih.gov/pubmed/37387144 http://dx.doi.org/10.1093/bioinformatics/btad220

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