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An Update on Anti-thrombotic Therapy Following Transcatheter Aortic Valve Implantation: Expert Cardiologist Opinion from a UK and Ireland Delphi Group

Transcatheter aortic valve implantation (TAVI) is an effective and established treatment for symptomatic aortic stenosis. However, there is a lack of consensus concerning the need for peri- and post-procedural anti-thrombotic medication. Contemporary guidelines recommend that anti-thrombotic therapy...

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Autores principales: Zaman, Azfar, Prendergast, Bernard, Hildick-Smith, David, Blackman, Daniel, Anderson, Richard, Spence, Mark S, Mylotte, Darren, Smith, David, Wilding, Ben, Chapman, Chris, Atkins, Kirsty, Pollock, Kevin G, Qureshi, Ayesha C, Banning, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311398/
https://www.ncbi.nlm.nih.gov/pubmed/37398870
http://dx.doi.org/10.15420/icr.2022.11
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author Zaman, Azfar
Prendergast, Bernard
Hildick-Smith, David
Blackman, Daniel
Anderson, Richard
Spence, Mark S
Mylotte, Darren
Smith, David
Wilding, Ben
Chapman, Chris
Atkins, Kirsty
Pollock, Kevin G
Qureshi, Ayesha C
Banning, Adrian
author_facet Zaman, Azfar
Prendergast, Bernard
Hildick-Smith, David
Blackman, Daniel
Anderson, Richard
Spence, Mark S
Mylotte, Darren
Smith, David
Wilding, Ben
Chapman, Chris
Atkins, Kirsty
Pollock, Kevin G
Qureshi, Ayesha C
Banning, Adrian
author_sort Zaman, Azfar
collection PubMed
description Transcatheter aortic valve implantation (TAVI) is an effective and established treatment for symptomatic aortic stenosis. However, there is a lack of consensus concerning the need for peri- and post-procedural anti-thrombotic medication. Contemporary guidelines recommend that anti-thrombotic therapy is balanced against a patient’s bleeding risk following TAVI, but do not fully consider the evolving evidence base. The purpose of the Delphi panel recommendations presented here is to provide a consensus elicited from a panel of experts who regularly prescribe anti-thrombotic therapy post-TAVI. The goal was to address evidence gaps across four key topics: anti-thrombotic therapy (anti-platelet and/or anti-coagulant) in TAVI patients in sinus rhythm; anti-thrombotic therapy in TAVI patients with AF; direct oral anti-coagulants versus vitamin K antagonists; and the need for UK/Ireland specific guidance. This consensus statement aims to inform clinical decision-making by providing a concise, evidence-based summary of best practice for prescribing anti-thrombotic therapies following TAVI and highlights areas where further research is needed.
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spelling pubmed-103113982023-07-01 An Update on Anti-thrombotic Therapy Following Transcatheter Aortic Valve Implantation: Expert Cardiologist Opinion from a UK and Ireland Delphi Group Zaman, Azfar Prendergast, Bernard Hildick-Smith, David Blackman, Daniel Anderson, Richard Spence, Mark S Mylotte, Darren Smith, David Wilding, Ben Chapman, Chris Atkins, Kirsty Pollock, Kevin G Qureshi, Ayesha C Banning, Adrian Interv Cardiol Structural Transcatheter aortic valve implantation (TAVI) is an effective and established treatment for symptomatic aortic stenosis. However, there is a lack of consensus concerning the need for peri- and post-procedural anti-thrombotic medication. Contemporary guidelines recommend that anti-thrombotic therapy is balanced against a patient’s bleeding risk following TAVI, but do not fully consider the evolving evidence base. The purpose of the Delphi panel recommendations presented here is to provide a consensus elicited from a panel of experts who regularly prescribe anti-thrombotic therapy post-TAVI. The goal was to address evidence gaps across four key topics: anti-thrombotic therapy (anti-platelet and/or anti-coagulant) in TAVI patients in sinus rhythm; anti-thrombotic therapy in TAVI patients with AF; direct oral anti-coagulants versus vitamin K antagonists; and the need for UK/Ireland specific guidance. This consensus statement aims to inform clinical decision-making by providing a concise, evidence-based summary of best practice for prescribing anti-thrombotic therapies following TAVI and highlights areas where further research is needed. Radcliffe Cardiology 2023-04-10 /pmc/articles/PMC10311398/ /pubmed/37398870 http://dx.doi.org/10.15420/icr.2022.11 Text en Copyright © 2023, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle Structural
Zaman, Azfar
Prendergast, Bernard
Hildick-Smith, David
Blackman, Daniel
Anderson, Richard
Spence, Mark S
Mylotte, Darren
Smith, David
Wilding, Ben
Chapman, Chris
Atkins, Kirsty
Pollock, Kevin G
Qureshi, Ayesha C
Banning, Adrian
An Update on Anti-thrombotic Therapy Following Transcatheter Aortic Valve Implantation: Expert Cardiologist Opinion from a UK and Ireland Delphi Group
title An Update on Anti-thrombotic Therapy Following Transcatheter Aortic Valve Implantation: Expert Cardiologist Opinion from a UK and Ireland Delphi Group
title_full An Update on Anti-thrombotic Therapy Following Transcatheter Aortic Valve Implantation: Expert Cardiologist Opinion from a UK and Ireland Delphi Group
title_fullStr An Update on Anti-thrombotic Therapy Following Transcatheter Aortic Valve Implantation: Expert Cardiologist Opinion from a UK and Ireland Delphi Group
title_full_unstemmed An Update on Anti-thrombotic Therapy Following Transcatheter Aortic Valve Implantation: Expert Cardiologist Opinion from a UK and Ireland Delphi Group
title_short An Update on Anti-thrombotic Therapy Following Transcatheter Aortic Valve Implantation: Expert Cardiologist Opinion from a UK and Ireland Delphi Group
title_sort update on anti-thrombotic therapy following transcatheter aortic valve implantation: expert cardiologist opinion from a uk and ireland delphi group
topic Structural
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311398/
https://www.ncbi.nlm.nih.gov/pubmed/37398870
http://dx.doi.org/10.15420/icr.2022.11
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