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Polygenic risk scores in pharmacogenomics: opportunities and challenges—a mini review

Pharmacogenomics (PGx) aims at tailoring drug therapy by considering patient genetic makeup. While drug dosage guidelines have been extensively based on single gene mutations (single nucleotide polymorphisms) over the last decade, polygenic risk scores (PRS) have emerged in the past years as a promi...

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Detalles Bibliográficos
Autores principales:	Simona, Aurélien, Song, Wenyu, Bates, David W., Samer, Caroline Flora
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311496/ https://www.ncbi.nlm.nih.gov/pubmed/37396043 http://dx.doi.org/10.3389/fgene.2023.1217049

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