Total Synthesis and Structural Studies of Zwitterionic Bacteroides fragilis Polysaccharide A1 Fragments

[Image: see text] Zwitterionic polysaccharides (ZPSs) are exceptional carbohydrates, carrying both positively charged amine groups and negatively charged carboxylates, that can be loaded onto MHC-II molecules to activate T cells. It remains enigmatic, however, how these polysaccharides bind to these...

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Detalles Bibliográficos
Autores principales: Wang, Zhen, Poveda, Ana, Zhang, Qingju, Unione, Luca, Overkleeft, Herman S., van der Marel, Gijsbert A., Jesús, Jiménez-Barbero, Codée, Jeroen D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311536/
https://www.ncbi.nlm.nih.gov/pubmed/37310804
http://dx.doi.org/10.1021/jacs.3c03976

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