Mapping Antibody Domain Exposure on Nanoparticle Surfaces Using DNA-PAINT

[Image: see text] Decorating nanoparticles with antibodies (Ab) is a key strategy for targeted drug delivery and imaging. For this purpose, the orientation of the antibody on the nanoparticle is crucial to maximize fragment antibody-binding (Fab) exposure and thus antigen binding. Moreover, the expo...

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Detalles Bibliográficos
Autores principales: Tholen, Marrit M. E., Rosier, Bas J. H. M., Vermathen, Robin T., Sewnath, Céline A. N., Storm, Cornelis, Woythe, Laura, Izquierdo-Lozano, Cristina, Riera, Roger, van Egmond, Marjolein, Merkx, Maarten, Albertazzi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311592/
https://www.ncbi.nlm.nih.gov/pubmed/37283555
http://dx.doi.org/10.1021/acsnano.3c02195

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