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Denoising Autoencoder Trained on Simulation-Derived Structures for Noise Reduction in Chromatin Scanning Transmission Electron Microscopy

[Image: see text] Scanning transmission electron microscopy tomography with ChromEM staining (ChromSTEM), has allowed for the three-dimensional study of genome organization. By leveraging convolutional neural networks and molecular dynamics simulations, we have developed a denoising autoencoder (DAE...

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Detalles Bibliográficos
Autores principales:	Alvarado, Walter, Agrawal, Vasundhara, Li, Wing Shun, Dravid, Vinayak P., Backman, Vadim, de Pablo, Juan J., Ferguson, Andrew L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311656/ https://www.ncbi.nlm.nih.gov/pubmed/37396862 http://dx.doi.org/10.1021/acscentsci.3c00178

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