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Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice

BACKGROUND: Knee osteoarthritis (KOA) has a complex pathological mechanism and is difficult to cure. The traditional medicine Du Huo Ji Sheng Tang (DHJST) has been used for the treatment of KOA for more than one thousand years, but its mechanism for treating KOA has not been revealed. In our previou...

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Detalles Bibliográficos
Autores principales:	Chen, Wen-jin, Zhuang, Yin, Peng, Wei, Cui, Wei, Zhang, Shu-jun, Wang, Jian-wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311838/ https://www.ncbi.nlm.nih.gov/pubmed/37386638 http://dx.doi.org/10.1186/s13020-023-00784-y

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