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The non-steroidal mineralocorticoid receptor antagonist finerenone and heart failure with preserved ejection fraction

Finerenone is a novel non-steroidal mineralocorticoid receptor (MR) antagonist (MRA) with high binding affinity, high MR selectivity and a short plasma half-life. In two major endpoint-driven clinical trials in patients with chronic kidney disease and type 2 diabetes mellitus (FIDELIO-DKD and FIGARO...

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Detalles Bibliográficos
Autores principales: Kintscher, Ulrich, Edelmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10311906/
https://www.ncbi.nlm.nih.gov/pubmed/37386461
http://dx.doi.org/10.1186/s12933-023-01899-0

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