Fentanyl-Induced Respiratory Depression and Locomotor Hyperactivity Are Mediated by μ-Opioid Receptors Expressed in Somatostatin-Negative Neurons

Opioid drugs are widely used as analgesics but cause respiratory depression, a potentially lethal side effect with overdose, by acting on μ-opioid receptors (MORs) expressed in brainstem regions involved in the control of breathing. Although many brainstem regions have been shown to regulate opioid-...

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Detalles Bibliográficos
Autores principales: Furdui, Andreea, da Silveira Scarpellini, Carolina, Montandon, Gaspard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312122/
https://www.ncbi.nlm.nih.gov/pubmed/37364996
http://dx.doi.org/10.1523/ENEURO.0035-23.2023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312122/
https://www.ncbi.nlm.nih.gov/pubmed/37364996
http://dx.doi.org/10.1523/ENEURO.0035-23.2023

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