Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels

Calcium and integrin-binding protein 2 (CIB2) and CIB3 bind to transmembrane channel-like 1 (TMC1) and TMC2, the pore-forming subunits of the inner-ear mechanoelectrical transduction (MET) apparatus. Whether these interactions are functionally relevant across mechanosensory organs and vertebrate spe...

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Detalles Bibliográficos
Autores principales: Giese, Arnaud P. J., Weng, Wei-Hsiang, Kindt, Katie S., Chang, Hui Ho Vanessa, Montgomery, Jonathan S., Ratzan, Evan M., Beirl, Alisha J., Rivera, Roberto Aponte, Lotthammer, Jeffrey M., Walujkar, Sanket, Foster, Mark P., Zobeiri, Omid A., Holt, Jeffrey R., Riazuddin, Saima, Cullen, Kathleen E., Sotomayor, Marcos, Ahmed, Zubair M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312449/
https://www.ncbi.nlm.nih.gov/pubmed/37398045
http://dx.doi.org/10.1101/2023.05.26.542533

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