Purinergic P2Y2 Receptor-Induced Activation of Endothelial TRPV4 Channels Mediates Lung Ischemia-Reperfusion Injury

Lung ischemia-reperfusion injury (IRI), characterized by inflammation, vascular permeability, and lung edema, is the major cause of primary graft dysfunction after lung transplantation. We recently reported that endothelial cell (EC) TRPV4 channels play a central role in lung edema and dysfunction a...

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Detalles Bibliográficos
Autores principales: Kuppusamy, Maniselvan, Ta, Huy Q., Davenport, Hannah N., Bazaz, Abhishek, Kulshrestha, Astha, Daneva, Zdravka, Chen, Yen-Lin, Carrott, Philip W., Laubach, Victor E., Sonkusare, Swapnil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312453/
https://www.ncbi.nlm.nih.gov/pubmed/37397979
http://dx.doi.org/10.1101/2023.05.29.542520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312453/
https://www.ncbi.nlm.nih.gov/pubmed/37397979
http://dx.doi.org/10.1101/2023.05.29.542520

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