Uracil-DNA Glycosylase of Murine Gammaherpesvirus 68 Binds Cognate Viral Replication Factors Independently of its Catalytic Residues

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Herpesviruses are large double-stranded DNA viruses that encode core replication proteins and accessory factors involved in nucleotide metabolism and DNA repair. Mammalian Uracil-DNA glycosylases (UNG) excise deleterious uracil residues from their genomic DNA. Each herpesvirus UNG studied to date ha...

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Detalles Bibliográficos
Autores principales: Smith, Kyle R., Paul, Somnath, Dong, Qiwen, Anannya, Orchi, Oldenburg, Darby G., Forrest, J. Craig, McBride, Kevin M., Krug, Laurie T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312458/
https://www.ncbi.nlm.nih.gov/pubmed/37398059
http://dx.doi.org/10.1101/2023.05.19.541466

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