The landscape of cancer rewired GPCR signaling axes

We explored the dysregulation of GPCR ligand signaling systems in cancer transcriptomics datasets to uncover new therapeutics opportunities in oncology. We derived an interaction network of receptors with ligands and their biosynthetic enzymes, which revealed that multiple GPCRs are differentially r...

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Detalles Bibliográficos
Autores principales: Arora, Chakit, Matic, Marin, DiChiaro, Pierluigi, Rosa, Natalia De Oliveira, Carli, Francesco, Clubb, Lauren, Fard, Lorenzo Amir Nemati, Kargas, Giorgos, Diaferia, Giuseppe, Vukotic, Ranka, Licata, Luana, Wu, Guanming, Natoli, Gioacchino, Gutkind, J. Silvio, Raimondi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312480/
https://www.ncbi.nlm.nih.gov/pubmed/37398064
http://dx.doi.org/10.1101/2023.03.13.532291

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