Learning structural heterogeneity from cryo-electron sub-tomograms with tomoDRGN

Cryo-electron tomography (cryo-ET) allows one to observe macromolecular complexes in their native, spatially contextualized environment. Tools to visualize such complexes at nanometer resolution via iterative alignment and averaging are well-developed but rely on assumptions of structural homogeneit...

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Detalles Bibliográficos
Autores principales: Powell, Barrett M., Davis, Joseph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312494/
https://www.ncbi.nlm.nih.gov/pubmed/37398315
http://dx.doi.org/10.1101/2023.05.31.542975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312494/
https://www.ncbi.nlm.nih.gov/pubmed/37398315
http://dx.doi.org/10.1101/2023.05.31.542975

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