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Learning structural heterogeneity from cryo-electron sub-tomograms with tomoDRGN
Cryo-electron tomography (cryo-ET) allows one to observe macromolecular complexes in their native, spatially contextualized environment. Tools to visualize such complexes at nanometer resolution via iterative alignment and averaging are well-developed but rely on assumptions of structural homogeneit...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312494/ https://www.ncbi.nlm.nih.gov/pubmed/37398315 http://dx.doi.org/10.1101/2023.05.31.542975 |