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Direct and indirect consequences of PAB1 deletion in the regulation of translation initiation, translation termination, and mRNA decay

Cytoplasmic poly(A)-binding protein (PABPC; Pab1 in yeast) is thought to be involved in multiple steps of post-transcriptional control, including translation initiation, translation termination, and mRNA decay. To understand these roles of PABPC in more detail for endogenous mRNAs, and to distinguis...

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Detalles Bibliográficos
Autores principales: Mangkalaphiban, Kotchaphorn, Ganesan, Robin, Jacobson, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312514/
https://www.ncbi.nlm.nih.gov/pubmed/37398227
http://dx.doi.org/10.1101/2023.05.31.543082