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MFGE8 inhibits insulin signaling through PTP1B

The role of integrins in regulating insulin signaling is incompletely understood. We have previously shown that binding of the integrin ligand milk fat globule epidermal growth factor like 8 (MFGE8) to the αvβ5 integrin promotes termination of insulin receptor signaling in mice. Upon ligation of MFG...

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Detalles Bibliográficos
Autores principales:	Datta, Ritwik, Podolsky, Michael J, Yang, Christopher D, Alba, Diana L., Singh, Sukhmani, Koliwad, Suneil, Lizama, Carlos O, Atabai, Kamran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312531/ https://www.ncbi.nlm.nih.gov/pubmed/37398282 http://dx.doi.org/10.1101/2023.05.30.542928

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