Foveal RGCs develop abnormal calcium dynamics weeks after photoreceptor ablation

OBJECTIVE OR PURPOSE: Physiological changes in retinal ganglion cells (RGCs) have been reported in rodent models of photoreceptor (PR) loss but this has not been investigated in primates. By expressing both a calcium indicator (GCaMP6s) and an optogenetic actuator (ChrimsonR) in foveal RGCs of the m...

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Detalles Bibliográficos
Autores principales: Xu, Zhengyang, Kunala, Karteek, Murphy, Peter, Puthussery, Teresa, McGregor, Juliette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312553/
https://www.ncbi.nlm.nih.gov/pubmed/37398439
http://dx.doi.org/10.1101/2023.05.30.542908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312553/
https://www.ncbi.nlm.nih.gov/pubmed/37398439
http://dx.doi.org/10.1101/2023.05.30.542908

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