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Evaluating the Performance of the Astral Mass Analyzer for Quantitative Proteomics Using Data Independent Acquisition

We evaluate the quantitative performance of the newly released Asymmetric Track Lossless (Astral) analyzer. Using data independent acquisition, the Thermo Scientific(™) Orbitrap(™) Astral(™) mass spectrometer quantifies 5 times more peptides per unit time than state-of-the-art Thermo Scientific(™) O...

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Detalles Bibliográficos
Autores principales: Heil, Lilian R., Damoc, Eugen, Arrey, Tabiwang N., Pashkova, Anna, Denisov, Eduard, Petzoldt, Johannes, Peterson, Amelia C., Hsu, Chris, Searle, Brian C., Shulman, Nicholas, Riffle, Michael, Connolly, Brian, MacLean, Brendan X., Remes, Philip M., Senko, Michael W., Stewart, Hamish I., Hock, Christian, Makarov, Alexander A., Hermanson, Daniel, Zabrouskov, Vlad, Wu, Christine C., MacCoss, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312564/
https://www.ncbi.nlm.nih.gov/pubmed/37398334
http://dx.doi.org/10.1101/2023.06.03.543570