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Genetic background influences the 5XFAD Alzheimer’s disease mouse model brain proteome
There is a pressing need to improve the translational validity of Alzheimer’s disease (AD) mouse models. Introducing genetic background diversity in AD mouse models has been proposed as a way to increase validity and enable discovery of previously uncharacterized genetic contributions to AD suscepti...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312637/ https://www.ncbi.nlm.nih.gov/pubmed/37398142 http://dx.doi.org/10.1101/2023.06.12.544646 |