Genetic background influences the 5XFAD Alzheimer’s disease mouse model brain proteome

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There is a pressing need to improve the translational validity of Alzheimer’s disease (AD) mouse models. Introducing genetic background diversity in AD mouse models has been proposed as a way to increase validity and enable discovery of previously uncharacterized genetic contributions to AD suscepti...

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Detalles Bibliográficos
Autores principales: Hurst, Cheyenne D., Dunn, Amy R., Dammer, Eric B., Duong, Duc M., Seyfried, Nicholas T., Kaczorowski, Catherine C., Johnson, Erik C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312637/
https://www.ncbi.nlm.nih.gov/pubmed/37398142
http://dx.doi.org/10.1101/2023.06.12.544646
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