Microglial P2Y(6) calcium signaling promotes phagocytosis and shapes neuroimmune responses in epileptogenesis

Microglial calcium signaling is rare in a baseline state but shows strong engagement during early epilepsy development. The mechanism and purpose behind microglial calcium signaling is not known. By developing an in vivo UDP fluorescent sensor, GRAB(UDP1.0), we discovered that UDP release is a conse...

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Detalles Bibliográficos
Autores principales: Umpierre, Anthony D., Li, Bohan, Ayasoufi, Katayoun, Zhao, Shunyi, Xie, Manling, Thyen, Grace, Hur, Benjamin, Zheng, Jiaying, Liang, Yue, Wu, Zhaofa, Yu, Xinzhu, Sung, Jaeyun, Johnson, Aaron J., Li, Yulong, Wu, Long-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312639/
https://www.ncbi.nlm.nih.gov/pubmed/37398001
http://dx.doi.org/10.1101/2023.06.12.544691

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