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Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase
Chitin is an abundant biopolymer and pathogen-associated molecular pattern that stimulates a host innate immune response. Mammals express chitin-binding and chitin-degrading proteins to remove chitin from the body. One of these proteins, Acidic Mammalian Chitinase (AMCase), is an enzyme known for it...
Autores principales: | Díaz, Roberto Efraín, Ecker, Andrew K., Correy, Galen J., Asthana, Pooja, Young, Iris D., Faust, Bryan, Thompson, Michael C., Seiple, Ian B., Van Dyken, Steven J., Locksley, Richard M., Fraser, James S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312649/ https://www.ncbi.nlm.nih.gov/pubmed/37398339 http://dx.doi.org/10.1101/2023.06.03.542675 |
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