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Incomplete Reprogramming of DNA Replication Timing in Induced Pluripotent Stem Cells

Induced pluripotent stem cells (iPSC) are a widely used cell system and a foundation for cell therapy. Differences in gene expression, DNA methylation, and chromatin conformation, which have the potential to affect differentiation capacity, have been identified between iPSCs and embryonic stem cells...

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Detalles Bibliográficos
Autores principales: Edwards, Matthew M., Wang, Ning, Massey, Dashiell J., Egli, Dieter, Koren, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312660/
https://www.ncbi.nlm.nih.gov/pubmed/37398435
http://dx.doi.org/10.1101/2023.06.12.544654