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SAD-1 kinase controls presynaptic phase separation by relieving SYD-2/Liprin-α autoinhibition

Neuronal development orchestrates the formation of an enormous number of synapses that connect the nervous system. In developing presynapses, the core active zone structure has been found to assemble through a liquid-liquid phase separation. Here, we find that the phase separation of SYD-2/Liprin-α,...

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Detalles Bibliográficos
Autores principales: McDonald, Nathan A., Tao, Li, Dong, Meng-Qiu, Shen, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312667/
https://www.ncbi.nlm.nih.gov/pubmed/37398223
http://dx.doi.org/10.1101/2023.06.12.544643