Dissection and Integration of Bursty Transcriptional Dynamics for Complex Systems

RNA velocity estimation is a potentially powerful tool to reveal the directionality of transcriptional changes in single-cell RNA-seq data, but it lacks accuracy, absent advanced metabolic labeling techniques. We developed a novel approach, TopicVelo, that disentangles simultaneous, yet distinct, dy...

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Detalles Bibliográficos
Autores principales: Gao, Cheng Frank, Vaikuntanathan, Suriyanarayanan, Riesenfeld, Samantha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312759/
https://www.ncbi.nlm.nih.gov/pubmed/37398022
http://dx.doi.org/10.1101/2023.06.13.544828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312759/
https://www.ncbi.nlm.nih.gov/pubmed/37398022
http://dx.doi.org/10.1101/2023.06.13.544828

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