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Overlooked Candida glabrata petites are echinocandin tolerant, induce host inflammatory responses, and display poor in vivo fitness

Small colony variants (SCVs) are relatively common among some bacterial species and are associated with poor prognosis and recalcitrant infections. Similarly, Candida glabrata – a major intracellular fungal pathogen – produces small and slow-growing respiratory-deficient colonies, termed “petite.” D...

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Detalles Bibliográficos
Autores principales: Arastehfar, Amir, Daneshnia, Farnaz, Hovhannisyan, Hrant, Fuentes, Diego, Cabrera, Nathaly, Quintin, Christopher, Ilkit, Macit, Ünal, Nevzat, Hilmioğlu-Polat, Suleyha, Jabeen, Kauser, Zaka, Sadaf, Desai, Jigar V., Lass-Flörl, Cornelia, Shor, Erika, Gabaldon, Toni, Perlin, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10312775/
https://www.ncbi.nlm.nih.gov/pubmed/37398397
http://dx.doi.org/10.1101/2023.06.15.545195